[Resource] SN megathread

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Roger

Roger

Arcanist
May 11, 2019
528
888
UK
The paper which appear in the answer above (https://www.ncbi.nlm.nih.gov/pubmed/27802417) has an interesting phrase in it:

"We conclude that the acute blood pressure-lowering effect of nitrite requires an acidic gastric environment. "

It appears that maybe specifically the blood pressure-lowering effect of SN are stronger on an acidic stomach. And it's not that PPIs specifically attack that, but antacids in general.
At least, that was my understanding.
It'll be interesting to see comment about this. Received wisdom has been that gastric acidity during the SN ingestion process is undesirable.

Anyway, does the hypotension thing really matter in the SN process ? The killing mechanism prevents the blood from transporting and releasing oxygen to the various organs of the body, including, crucially, the brain, and the increased heart rate plus hypotension (low BP) are really irrelevant to the oxygen exchange deficit.

Just a thought.
 
Jinx

Jinx

-
May 15, 2019
13
17
If you have enough pills you could maybe try dosing 20-30mg to test for side effects, bare in mind drugs have different side effects for each individual.

I’m planning on testing mine out tomorrow; will report back. Experiencing no side effects is ideal assuming it actually is Meto
I don't have that many pills and am rationing them so I'll have enough left over in case something unexpected happens where I would have to cancel my attempt and try again another time. Even for my last dose I think I'll probably only go with 20mg. I'm usually kind of sensitive to meds which I guess is why I felt some doubt.

Good luck with your test, I hope it goes just as well.
 
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P

Pointlesslife

I'm feel dead and lifeless already so why live
Nov 7, 2018
61
165
I have a problem with getting the SN and meto delivered to my house. I wouldn't want my mom or brother (who I live with) to know I bought them. Any advice on how to get around this problem?
 
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pane

pane

Wise
Apr 29, 2019
248
359
I have a problem with getting the SN and meto delivered to my house. I wouldn't want my mom or brother (who I live with) to know I bought them. Any advice on how to get around this problem?
UPS stores and other companies offer private mailbox services. Go to Google and type in "private mailbox your city/town" and you should be able to find them,
 
M

malummo

Member
Jul 15, 2019
61
90
It'll be interesting to see comment about this.
fast absorption of nitrite is essential, and this is achieved by acid reducer, meto and fasting. avoiding lingering in the stomach. a recent post about the interaction of nitrite and acid reducer has been made, as far as i can remember absorption is accelerated by 50% (should be checked) nitrite is rapidly converted to nitrate in the blood causing methemoglobinemia and it is the aim of this method. under the influence of an acidic environment in the stomach, nitrite is converted to nitric oxide, which lowers blood pressure but also reduces nitrite concentration. therapeutic amounts of SN for lowering blood pressure are low and gastric alkalinity may reduce this but I doubt it will affect the fatal dose of SN since methemoglobinemia already above 20% in plasma lowers blood pressure.
ups, sorry
 
P

Pointlesslife

I'm feel dead and lifeless already so why live
Nov 7, 2018
61
165
Maybe I open a po box at one location. Have sodium nitrite shipped to it. Then close that po box and open one at another location. Ship meto to it. I don't like having both sent to one po box cuz to me it wouldn't be hard for them to suspect they are being used for suicide and I really don't want to be under suspicion for possible suicide.
 
Lennox

Lennox

No alarms, and no surprises...
Jul 21, 2019
144
265
It'll be interesting to see comment about this. Received wisdom has been that gastric acidity during the SN ingestion process is undesirable.

Anyway, does the hypotension thing really matter in the SN process ? The killing mechanism prevents the blood from transporting and releasing oxygen to the various organs of the body, including, crucially, the brain, and the increased heart rate plus hypotension (low BP) are really irrelevant to the oxygen exchange deficit.

Just a thought.
I suppose that, in the case of CTB'ing, the hypotension specifically will happen regardless of minimal impacts of antacids. Because the quantity taken to CTB (15~20g) is much much larger than the quantity administered in the study (0.3 mg kg-1 , which for a 70kg man would mean 21mg).

But the main point I was trying to get at is that, it doesn't seem to have been established that the interaction between PPIs and SN is necessarily different from the interaction between other types of antacids and SN. The paper doesn't seem to conclude that only the PPI class of antacids will cut down effects of SN, but only say that an acidic stomach seems to be important for the hypotension effect of SN. So, it seems to me any type of antacid could potentially play the same role here.

All that said, I haven't researched the issue further yet, I'm basing my conclusions off this paper alone.
 
Plushy

Plushy

Member
Jan 22, 2019
32
98
Is it really necessary to take pills and to fast days before taking SN. I saw someone say that you don't need to take 2 days to take pills, only 8 or so hours.
 
L

Lifeisatrap

Specialist
Oct 5, 2018
398
1,696
soes anyone know what the dosages/regimen would be with prochlorperazine instead of metoclopramide? i might be able to get some prochlorperazine at a push but i dont know how the dosages would be affected. any help would be appreciated :)
I second this. Was luckily able to get a hold of this along with zofran. But haven't tested it out yet because i'm scared of possible eps symptoms and it's more potent than meto. Have experienced eps symptoms such as muscle spasms in the past from various meds so i'm hesitant:(
 
N

ningaman151

Veteran
Jul 28, 2018
195
12
Can anyone please provide me with complete instructions for this method. I have found a supplier with 99.5% purity of sodium nitrite. Please I want to ctb the pain has been going on for too long.
 
F

FinalTime

Member
Jun 30, 2018
10
3
Vomiting is unlikely with N. For SN going without meto or domperidone is just setting yourself up for a bad time.
Sorry to pester with questions, but could you define "a bad time"? I don't mind so much a painful exit just so long as it works.
 
P

Pointlesslife

I'm feel dead and lifeless already so why live
Nov 7, 2018
61
165
Sorry to pester with questions, but could you define "a bad time"? I don't mind so much a painful exit just so long as it works.
I am pretty sure he means you will just end up pucking the SN out and not die. Meto is crucial with this method.
 
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F

FinalTime

Member
Jun 30, 2018
10
3
I am pretty sure he means you will just end up pucking the SN out and not die. Meto is crucial with this method.
Initially that's what I thought too, but I noticed that in another thread Jake3d posted it was still likely to kill you even without the antiemetic, though it would still be a "bad time". Really just looking for some clarification on it.
 
A

Aion

Member
Jul 20, 2019
23
27
20
Initially that's what I thought too, but I noticed that in another thread Jake3d posted it was still likely to kill you even without the antiemetic, though it would still be a "bad time". Really just looking for some clarification on it.
You will most likely die even if you puke. But it will take hours and hours, and you might suffer a lot.
 
Last edited:
onlyinsleep

onlyinsleep

I can see their faces
Jun 3, 2019
46
62
You will most likely die even if you puke. But it will take hours and hours, and you might suffer a lot.
I hate the prep this method needs. I'm ready to go on a whim usually. I can't believe we need 48 hours. I wish N was more accessible.
 
F

Fr2

-
Jun 15, 2019
87
175
Is it possible to calculate the optimal quantity of SN based on the person's weight?
 
Last edited:
littlelady856

littlelady856

ribbit
Dec 20, 2018
368
1,940
Is anyone worried about feeling super dehydrated after drinking SN?
 
LifeOver

LifeOver

Professional Suicide Attempter
Jul 23, 2019
117
246
bus station: waiting for a bus
Does a stat dose of meto before taking SN work or is the 48 hour regime absolutely necessary?

Also, is the fasting before taking SN necessary bc I do not want to be too suspicious to my family.
 
T

thrwaway99

Member
Mar 24, 2019
81
195
I personally believe that stat dose works. The wild pigs don't consume any anti-nausea pills before their lethal hog-gones and SN still 'works.' But I'm on the fence about stat or regimen because I have no proper data to base my assumptions on regarding metoclopramide. The stat dose is nice as it's impulsive. Maybe suicides aren't the most patient people around in general so I bet there has to be a successful stat-doser out there somewhere. But be that as it may I am not against following a regimen.
 
irrelevant_string

irrelevant_string

Member
Jun 16, 2019
76
139
Is it possible to calculate the optimal quantity of SN based on the person's weight?
Here's a discussion about the recommended dose:

I haven't been able to find anything useful other than that.
I don't think there's any precise information about the optimal dose, all we know is the minimum lethal dose(71mg/kg) which you then multiply by some arbitrary number just to be sure. 25g seems to be the upper boundary. Personally, I wouldn't take more than 20g.
 
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onlyinsleep

onlyinsleep

I can see their faces
Jun 3, 2019
46
62
Here's a discussion about the recommended dose:

I haven't been able to find anything useful other than that.
I don't think there's any precise information about the optimal dose, all we know is the minimum lethal dose(71mg/kg) which you then multiply by some arbitrary number just to be sure. 25g seems to be the upper boundary. Personally, I wouldn't take more than 20g.
How much loreazapam Benzos you need to avoid seizures? I don't wanna fall seizing off a bed and wake them.
 
irrelevant_string

irrelevant_string

Member
Jun 16, 2019
76
139
I'm not sure. There are a few things to consider. One being - previous use of benzos as you'd have built some tolerance to them that way and weight plays a role too.
Also, you don't wanna take too much and incapacitate yourself to the point that you can't even drink SN.
I don't have a good answer or any sources to back up my claims. I'm only taking guesses based on personal experience.
I have a long history of benzo usage. I've been taking 1mg of lorazepam before bed for a few months now(I've been on xanax before that) and it still works, though not as fast as it used to, it takes about an hour to feel the effect now. I'd take maybe 5mg half an hour before taking SN.
I weigh somewhere around 45-50kg.
 
J

jake3d

Illuminated
May 29, 2019
1,045
2,085
Europe
Is it possible to calculate the optimal quantity of SN based on the person's weight?
Yeah. Wikipedia lists lowest known lethal dose as 72mg/kg. Triple that and you will get pretty close to the 15-25g most people decide to take.
 
C

Codieb1

Veteran
Jun 18, 2019
179
295
Does the body build up a resistance to SN? I was thinking of taking small amounts and gradually increasing every few days. Best case scenario, I "accidentally" die. Worst case, I suffer after effects. Basically what I'm asking is, will I get a tolerance to vomiting, aftereffects, or methoglobwhatsitcalled, or is tolerance to this just not a thing? Is this worth trying at all, or should I just forget it? Basically I wanted to try 5g tonight just to see what would happen, but if this is dumb, never mind. I'd be taking meto of course.
 
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