(SN) How do dopamine blockers prevent you from vomiting

  • Thread starter pentobarbitaldreams
  • Start date
  • Welcome to Sanctioned Suicide, a pro-choice forum for the discussion of mental illness, suicide, and the moral implications of the act itself. This is not a pro-suicide site. We do not encourage or aid suicide, and the information offered is for educational purposes only. Read our rules and FAQ for more information. We also offer a recovery subforum if you wish to get support.

    You can close this box by clicking the top right "X".

pentobarbitaldreams

pentobarbitaldreams

Member
Jun 11, 2020
77
217
I’m planning on using SN. I’m on paliperidone (antipsychotic) and one of the guides said that it fully replaces a need for antiemetic. However, I asked some fellow schizophrenics online and they say they’ve vomited while on paliperidone before (though not while taking SN). My question is what makes paliperidone work for keeping SN down but not other stuff?
 
L

Living sucks

no one can understand
Mar 27, 2020
2,919
2,831
There is no guarantee that any AE or AP will stop you from vomiting SN or anything.

Some take AEs and vomit, some don’t take a AE and don’t vomit.
Can’t take AE with an AP.

it is all explained in the SN Resource guide that has been linked to you previously
 
TonyThat2003

TonyThat2003

Member
Jun 1, 2020
23
28
Your question makes no sense, the antiemetics will try to prevent you of vomiting anything that you have on your stomach. And its not 100% effective, everyone has a different organism so drugs work differently on everyone.
 
autumnal

autumnal

Illuminated
Feb 5, 2020
1,665
3,038
Australia
I’m planning on using SN. I’m on paliperidone (antipsychotic) and one of the guides said that it fully replaces a need for antiemetic. However, I asked some fellow schizophrenics online and they say they’ve vomited while on paliperidone before (though not while taking SN). My question is what makes paliperidone work for keeping SN down but not other stuff?
Stan's Guide, the forum's definitive resource on the SN method, lists paliperidone as one of the 13 antipsychotics which do provide an antiemetic effect. Although intended primarily as antipsychotics, these medications also provide antiemetic effects due to their dopamine-blocking qualities.



Per the image above, different mechanisms in the brain are responsible for vomiting due to different triggers. The chemoreceptor trigger zone (CTZ) governs vomiting triggered by drugs/chemicals/toxins (and thus SN)(see red box). Drugs which help suppress this reaction include dopamine antagonists (blockers). However, vomiting caused by the other two sets of triggers listed (see green and blue boxes) is reduced by other kinds of medications.

So there are a few explanations for your friend who vomited while on paliperidone:
  • His vomiting was triggered by one of the causes listed in the green or blue boxes, which paliperidone does not reduce.
  • His vomiting was triggered by one of the causes in the red box because his dosage and/or time spent on paliperidone was insufficient to have the usual antiemetic effects.
  • His vomiting was triggered by one of the causes in the red box because even though his dosage and time spent on the medication were sufficient, these things can still happen as antiemetics only reduce the chances of vomiting but do not ever completely remove it.
  • Even with an appropriate antiemetic at an appropriate dosage, the chances of vomiting also increase the larger the amount of stimulus is (i.e drugs/chemicals/toxins). So perhaps your friend took such a massive amount of drugs/chemicals/toxins that it overwhelmed the antiemetic effects.
 
Thread starter Similar threads Forum Replies Date
Mustkeyknow SN - How do I NOT ask for help? Suicide Discussion 11
T How Do You Prepare? Suicide Discussion 1
LavenderMemories How to say goodbye to someone you love? Suicide Discussion 3
illbeinthegarage [Venting] how to stop myself from an impulsive attempt Suicide Discussion 3
helpmehelpme How do you emotionally prepare family? Suicide Discussion 11
Theregoesthatidea People who have lied for drugs you could use to ctb, how did you do it Suicide Discussion 16
Red87 How long does it take to go unconscious with sn Suicide Discussion 2
End_Game Do I need to know how to swim to do shallow water blackout? Suicide Discussion 1
B How do you know when it’s time ? Suicide Discussion 14
_Minsk anyone else hating when people ask you how you're doin? Suicide Discussion 18
D [Discussion] How hard it is to die by slit throat? Suicide Discussion 11
ManWithNoName [Discussion] How accurate is this guy? Suicide Discussion 11
F How do you convince a sensitive person that it wasn't their fault? Suicide Discussion 1
W How do you be brave Suicide Discussion 8
S how many helium balloons in a car so u can get asphyxia ? Suicide Discussion 8
_Minsk [Venting] How is it even possible to get out of this swamp if there's nothing else? Suicide Discussion 2
tmcglone25 How long does SN take to work? Suicide Discussion 2
TheSoulless [Venting] How am I supposed to enjoy life again? Suicide Discussion 5
Stevenstevensteven How fucked up am i? Suicide Discussion 16
eiyuu [Discussion] How do you know? Suicide Discussion 15
TimeToBiteTheDust "Life is beautiful no matter how hard it is" Suicide Discussion 44
S Can’t believe this is how I’m spending my 20th birthday Suicide Discussion 16
aliceinwonderland How Much N do you need depending on your weight? Suicide Discussion 5
catsarecool How to protect my loved ones from the pain? Suicide Discussion 3
E How long have you wanted to CTB? Suicide Discussion 36
iDieUDie80 [Help] How to overcome the fear of post-existence/post-consciousness? Suicide Discussion 19
W How Can I Do This to My Parents? Suicide Discussion 18
overwhelming [Discussion] How does one successfully hide their depression? Suicide Discussion 8
anonymousapple [Help] How long can Metoclopramide be stored safely? Suicide Discussion 2
J [Help] How to prepare before i CTB? Suicide Discussion 7
Finally_Free [Discussion] How to deal with the perspective of people who love us being traumatized by we CTBing? Suicide Discussion 9
J How to ensure medics won’t “save” you after a suicide attempt Suicide Discussion 23
rhiino Who lost a loved one to suicide / how has it affected you? Suicide Discussion 14
E How do i get N from A? Suicide Discussion 6
B How long will sn last if I order it Suicide Discussion 9
anonymousapple How effective is Risperidone in SN method? Suicide Discussion 14
Finally_Free [Help] How to calibrate a cheap precision scale for SN method? Suicide Discussion 0
TimeToBiteTheDust [Venting] Pisces the most depressive? How many here? Suicide Discussion 26
H How can I numb physical pain so I could ctb through cutting ? Suicide Discussion 6
A [Help] How early do you think I could ctb at a hotel without getting caught? Suicide Discussion 6
Close_to_freedom Without distractions how are you able to live? Suicide Discussion 0
Close_to_freedom What are your current distractions and how much longer do you think they’ll distract you? Suicide Discussion 20
Q How do I kill myself Suicide Discussion 14
_Minsk [Discussion] how long has it been going like this?.. Suicide Discussion 9
KuRsAnI [Method] How necessary is an antiemetic for the SN method? Suicide Discussion 10
S [Discussion] How do you know when you've had enough? Suicide Discussion 3
Iwouldratherdie How to pay for a hotel at checkout? Suicide Discussion 28
B How can you access dark web? Suicide Discussion 6
I [Venting] how to take xanax properly ? Suicide Discussion 4
WarRunner [Discussion] How painful would be a neck slice be? Suicide Discussion 3
Similar threads